The electrochemical properties of Al-Zn-In-Mg-Ti alloys with different Fe content was studied by electrochemical method, galvanic corrosion and ICP-MS in seawater. The results show that the Al-5Zn-0.02In-1Mg-0.05Ti-0.1Fe(wt.%) alloy present the enough negative open circuit potential, the good polarization properties, the properties of low resistance and high capacitance. The coupling potential is negative and stable. The coupling current is higher. The dissolved amount of Al and Zn are 22ug/L and 3.8ug/L at 2h. The current’s peak values of 48h is 36A. It means that the number of active points and dissolution uniformity of aluminum alloy are improved. While Fe content exceeds 0.1wt.%, the resistance of active dissolution increases gradually, which indicates that the activation of In is limited. It is found that Al-Zn-In-Mg-Ti alloy owns better electrochemical properties with 0.1wt.% Fe.