To increase anti-skidding performance of highway asphalt pavement and solve scarcity of high quality aggregates, and then acid aggregates can be widely used in anti-skidding layer of asphalt pavement. The boiling water test was used to investigate adhesiveness between silica and asphalt added different contents of hydrated lime. Based upon the design theory of graded anti-skidding asphalt mixtures, the coarse aggregates retained on the 4.75mm sieve were adopted by silica, fine aggregates passing the 4.75mm sieve and filler were utilized by limestone. Marshall design method was performed to determine gradation composition design of asphalt mixtures containing silica, the laboratory performance tests were conducted to verify the gradation composition design of the mixtures. Then, the experimental section of asphalt pavement containing silica is chosen for construction and tracking detection at a typical region. The results show adhesiveness between silica and asphalt can be improved by the addition of hydrated lime at 2% by the weight of asphalt. The performance test results of asphalt mixtures containing silica added 2% hydrated lime replacing the same weight of filler can meet the requirements of the technical specifications (JTG F40-2004) especially that presents favorable moisture susceptibility. The experimental pavement conditions display an appreciable usage. The texture depth and British pendulum numbers of experimental pavement is higher than that of common asphalt pavement at the same route. Moreover, the texture depth and British pendulum numbers along with increasing time exhibit lower decrease than that of common asphalt pavement in terms of tracking detection results. This means silica, as a kind of acid aggregate, may be used in the highway asphalt pavement using appropriate gradations composition design and anti-stripping agent, ant that can improve the skidding resistance of asphalt pavement.